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Metformin Improves Diabetic Bone Health by Re-Balancing Catabolism and Nitrogen Disposal

OBJECTIVE: Metformin, a leading drug used to treat diabetic patients, is reported to benefit bone homeostasis under hyperglycemia in animal models. However, both the molecular targets and the biological pathways affected by metformin in bone are not well identified or characterized. The objective of...

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Detalles Bibliográficos
Autores principales: Li, Xiyan, Guo, Yuqi, Yan, Wenbo, Snyder, Michael P., Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696809/
https://www.ncbi.nlm.nih.gov/pubmed/26716870
http://dx.doi.org/10.1371/journal.pone.0146152