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Metformin Improves Diabetic Bone Health by Re-Balancing Catabolism and Nitrogen Disposal
OBJECTIVE: Metformin, a leading drug used to treat diabetic patients, is reported to benefit bone homeostasis under hyperglycemia in animal models. However, both the molecular targets and the biological pathways affected by metformin in bone are not well identified or characterized. The objective of...
Autores principales: | Li, Xiyan, Guo, Yuqi, Yan, Wenbo, Snyder, Michael P., Li, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696809/ https://www.ncbi.nlm.nih.gov/pubmed/26716870 http://dx.doi.org/10.1371/journal.pone.0146152 |
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