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Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins

Mitochondria are highly dynamic subcellular organelles participating in many signaling pathways such as antiviral innate immunity and cell death cascades. Here we found that mitochondrial fusion was impaired in dengue virus (DENV) infected cells. Two mitofusins (MFN1 and MFN2), which mediate mitocho...

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Detalles Bibliográficos
Autores principales: Yu, Chia-Yi, Liang, Jian-Jong, Li, Jin-Kun, Lee, Yi-Ling, Chang, Bi-Lan, Su, Chan-I, Huang, Wei-Jheng, Lai, Michael M. C., Lin, Yi-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696832/
https://www.ncbi.nlm.nih.gov/pubmed/26717518
http://dx.doi.org/10.1371/journal.ppat.1005350