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Stimulus-specific combinatorial functionality of neuronal c-fos enhancers

The c-fos gene is induced by a broad range of stimuli, and has been commonly used as a reliable marker for neural activity. Its induction mechanism and available reporter mouse lines are exclusively based on the c-fos promoter activity. Here, we demonstrate that multiple enhancers surrounding the c-...

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Detalles Bibliográficos
Autores principales: Joo, Jae-Yeol, Schaukowitch, Katie, Farbiak, Lukas, Kilaru, Gokhul, Kim, Tae-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696896/
https://www.ncbi.nlm.nih.gov/pubmed/26595656
http://dx.doi.org/10.1038/nn.4170