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AAV1.NT-3 gene therapy attenuates spontaneous autoimmune peripheral polyneuropathy

The spontaneous autoimmune peripheral polyneuropathy (SAPP) model in B7-2 knockout non-obese diabetic mice shares clinical and histological features with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Secondary axonal loss is prominent in the progressive phase of this neuropathy....

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Detalles Bibliográficos
Autores principales: Yalvac, M E, Arnold, W D, Braganza, C, Chen, L, Mendell, J R, Sahenk, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696906/
https://www.ncbi.nlm.nih.gov/pubmed/26125608
http://dx.doi.org/10.1038/gt.2015.67