Cargando…

AAV1.NT-3 gene therapy attenuates spontaneous autoimmune peripheral polyneuropathy

The spontaneous autoimmune peripheral polyneuropathy (SAPP) model in B7-2 knockout non-obese diabetic mice shares clinical and histological features with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Secondary axonal loss is prominent in the progressive phase of this neuropathy....

Descripción completa

Detalles Bibliográficos
Autores principales:	Yalvac, M E, Arnold, W D, Braganza, C, Chen, L, Mendell, J R, Sahenk, Z
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696906/ https://www.ncbi.nlm.nih.gov/pubmed/26125608 http://dx.doi.org/10.1038/gt.2015.67

Ejemplares similares

AAV1.NT-3 Gene Therapy for Charcot–Marie–Tooth Neuropathy
por: Sahenk, Zarife, et al.
Publicado: (2014)

AAV1.NT-3 gene therapy prevents age-related sarcopenia
por: Ozes, Burcak, et al.
Publicado: (2023)

AAV1.NT-3 gene therapy for X-linked Charcot–Marie–Tooth neuropathy type 1
por: Ozes, Burcak, et al.
Publicado: (2021)

Systemic IGF-1 gene delivery by rAAV9 improves spontaneous autoimmune peripheral polyneuropathy (SAPP)
por: Gao, Tong, et al.
Publicado: (2018)

AAV1.NT‐3 gene therapy in the SOD1KO mouse model of accelerated sarcopenia
por: Tong, Lingying, et al.
Publicado: (2023)

AAV1.NT-3 gene therapy in a CMT2D model: phenotypic improvements in Gars(P278KY/+) mice
por: Ozes, Burcak, et al.
Publicado: (2021)

Fingolimod therapy is not effective in a mouse model of spontaneous autoimmune peripheral polyneuropathy
por: Huehnchen, Petra, et al.
Publicado: (2018)

Development of Spontaneous Autoimmune Peripheral Polyneuropathy in B7-2–Deficient Nod Mice
por: Salomon, Benoît, et al.
Publicado: (2001)

A new animal model of spontaneous autoimmune peripheral polyneuropathy: implications for Guillain-Barré syndrome
por: Yang, Mu, et al.
Publicado: (2014)

Elimination of activating Fcγ receptors in spontaneous autoimmune peripheral polyneuropathy model protects from neuropathic disease
por: Zhang, Gang, et al.
Publicado: (2019)

Follistatin Gene Therapy Improves Ambulation in Becker Muscular Dystrophy
por: Al-Zaidy, Samiah A., et al.
Publicado: (2015)

AAV-mediated NT-3 overexpression protects cochleae against noise-induced synaptopathy
por: Chen, Hengchao, et al.
Publicado: (2018)

Current Clinical Applications of In Vivo Gene Therapy with AAVs
por: Mendell, Jerry R., et al.
Publicado: (2021)

Testing preexisting antibodies prior to AAV gene transfer therapy: rationale, lessons and future considerations
por: Mendell, Jerry R., et al.
Publicado: (2022)

AAV.Dysferlin Overlap Vectors Restore Function in Dysferlinopathy Animal Models
por: Sondergaard, Patricia C, et al.
Publicado: (2015)

AAV2-Mediated Subretinal Gene Transfer of hIFN-α Attenuates Experimental Autoimmune Uveoretinitis in Mice
por: Tian, Lichun, et al.
Publicado: (2011)

Inhibition of experimental autoimmune uveitis by intravitreal AAV-Equine-IL10 gene therapy
por: Crabtree, Elizabeth, et al.
Publicado: (2022)

Subacute Sensorimotor Polyneuropathy Associated with Autoimmune Hepatitis
por: Park, Kee Hong, et al.
Publicado: (2016)

Treatment of experimental autoimmune encephalomyelitis using AAV gene therapy by blocking T cell costimulatory pathways
por: Zhong, Chen, et al.
Publicado: (2022)

AAV2-Mediated Subretinal Gene Transfer of mIL-27p28 Attenuates Experimental Autoimmune Uveoretinitis in Mice
por: Shao, Ju, et al.
Publicado: (2012)

Systemic delivery of AAVrh74.tMCK.hCAPN3 rescues the phenotype in a mouse model for LGMD2A/R1
por: Sahenk, Zarife, et al.
Publicado: (2021)

Antidepressant effect of recombinant NT4-NAP/AAV on social isolated mice through intranasal route
por: Liu, Fei, et al.
Publicado: (2016)

Anti-AAV Antibodies in AAV Gene Therapy: Current Challenges and Possible Solutions
por: Weber, Thomas
Publicado: (2021)

Immunogenicity and toxicity of AAV gene therapy
por: Ertl, Hildegund C. J.
Publicado: (2022)

AAV gene therapy vectors in the TMJ
por: Brouxhon, Sabine M., et al.
Publicado: (2022)

Acute Inflammatory Demyelinating Polyneuropathy (AIDP) Masked by Autoimmune Thyroiditis
por: Wirtshafter, Stephanie, et al.
Publicado: (2021)

Peripheral polyneuropathy after bariatric surgery for morbid obesity
por: Lin, I-Ching, et al.
Publicado: (2011)

Peripheral Nerve Enlargement in Chronic Inflammatory Demyelinating Polyneuropathy
por: Tanitame, Keizo, et al.
Publicado: (2020)

AAV Targeting of Glial Cell Types in the Central and Peripheral Nervous System and Relevance to Human Gene Therapy
por: O’Carroll, Simon J., et al.
Publicado: (2021)

Pre-clinical Safety and Off-Target Studies to Support Translation of AAV-Mediated RNAi Therapy for FSHD
por: Wallace, Lindsay M., et al.
Publicado: (2017)

Impaired regeneration in calpain-3 null muscle is associated with perturbations in mTORC1 signaling and defective mitochondrial biogenesis
por: Yalvac, Mehmet E., et al.
Publicado: (2017)

Editorial: “AAV Gene Therapy: Immunology and Immunotherapeutics”
por: Martinez-Navio, José M., et al.
Publicado: (2021)

Editorial: Immunogenicity and toxicity of AAV gene therapy
por: Bradbury, Allison, et al.
Publicado: (2023)

A Rare Case of Autoimmune Demyelinating Polyneuropathy and Hydrocephalus Secondary to Pembrolizumab
por: Arora, Aakriti, et al.
Publicado: (2020)

Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems
por: Chan, Ken Y, et al.
Publicado: (2017)

Peripheral Polyneuropathy and Cognitive Impairment in Type II Diabetes Mellitus
por: Elsharkawy, Rasha Elbialy, et al.
Publicado: (2021)

A Splice Variant of GNB3 and Peripheral Polyneuropathy in Type 1 Diabetes
por: Chistiakov, Dimitry A., et al.
Publicado: (2009)

Efficient gene transduction in pigs and macaques with the engineered AAV vector AAV.GT5 for hemophilia B gene therapy
por: Kashiwakura, Yuji, et al.
Publicado: (2023)

IVIg for apparently autoimmune small-fiber polyneuropathy: first analysis of efficacy and safety
por: Liu, Xiaolei, et al.
Publicado: (2018)

Immunological Monitoring to Rationally Guide AAV Gene Therapy
por: Britten, Cedrik Michael, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_2m5qpa5tm7p20b99v2s79o8o1e