Pinpointing RNA-Protein Cross-Links with Site-Specific Stable Isotope-Labeled Oligonucleotides

[Image: see text] High affinity RNA-protein interactions are critical to cellular function, but directly identifying the determinants of binding within these complexes is often difficult. Here, we introduce a stable isotope mass labeling technique to assign specific interacting nucleotides in an oli...

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Detalles Bibliográficos
Autores principales: Lelyveld, Victor S., Björkbom, Anders, Ransey, Elizabeth M., Sliz, Piotr, Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697197/
https://www.ncbi.nlm.nih.gov/pubmed/26583201
http://dx.doi.org/10.1021/jacs.5b10596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697197/
https://www.ncbi.nlm.nih.gov/pubmed/26583201
http://dx.doi.org/10.1021/jacs.5b10596

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