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Pinpointing RNA-Protein Cross-Links with Site-Specific Stable Isotope-Labeled Oligonucleotides
[Image: see text] High affinity RNA-protein interactions are critical to cellular function, but directly identifying the determinants of binding within these complexes is often difficult. Here, we introduce a stable isotope mass labeling technique to assign specific interacting nucleotides in an oli...
Autores principales: | Lelyveld, Victor S., Björkbom, Anders, Ransey, Elizabeth M., Sliz, Piotr, Szostak, Jack W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2015
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697197/ https://www.ncbi.nlm.nih.gov/pubmed/26583201 http://dx.doi.org/10.1021/jacs.5b10596 |
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