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Alternative 3'UTRs act as scaffolds to regulate membrane protein localization

About half of human genes use alternative cleavage and polyadenylation (ApA) to generate mRNA transcripts that differ in the length of their 3' untranslated regions (3'UTRs) while producing the same protein (1–3). Here we show in human cell lines that alternative 3' UTRs differentiall...

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Detalles Bibliográficos
Autores principales: Berkovits, Binyamin D., Mayr, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697748/
https://www.ncbi.nlm.nih.gov/pubmed/25896326
http://dx.doi.org/10.1038/nature14321