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Small Rad51 and Dmc1 Complexes Often Co-occupy Both Ends of a Meiotic DNA Double Strand Break

The Eukaryotic RecA-like proteins Rad51 and Dmc1 cooperate during meiosis to promote recombination between homologous chromosomes by repairing programmed DNA double strand breaks (DSBs). Previous studies showed that Rad51 and Dmc1 form partially overlapping co-foci. Here we show these Rad51-Dmc1 co-...

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Detalles Bibliográficos
Autores principales: Brown, M. Scott, Grubb, Jennifer, Zhang, Annie, Rust, Michael J., Bishop, Douglas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697796/
https://www.ncbi.nlm.nih.gov/pubmed/26719980
http://dx.doi.org/10.1371/journal.pgen.1005653