Cargando…
Novel Zn(2+) Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents
Type 2 diabetes (T2D) occurs when there is insufficient insulin release to control blood glucose, due to insulin resistance and impaired β-cell function. The GPR39 receptor is expressed in metabolic tissues including pancreatic β-cells and has been proposed as a T2D target. Specifically, GPR39 agoni...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697807/ https://www.ncbi.nlm.nih.gov/pubmed/26720709 http://dx.doi.org/10.1371/journal.pone.0145849 |