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Trichinella spiralis Paramyosin Binds Human Complement C1q and Inhibits Classical Complement Activation

BACKGROUND: Trichinella spiralis expresses paramyosin (Ts-Pmy) as a defense mechanism. Ts-Pmy is a functional protein with binding activity to human complement C8 and C9 and thus plays a role in evading the attack of the host’s immune system. In the present study, the binding activity of Ts-Pmy to h...

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Detalles Bibliográficos
Autores principales: Sun, Ran, Zhao, Xi, Wang, Zixia, Yang, Jing, Zhao, Limei, Zhan, Bin, Zhu, Xinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697845/
https://www.ncbi.nlm.nih.gov/pubmed/26720603
http://dx.doi.org/10.1371/journal.pntd.0004310