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The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling

CC2D1A and CC2D1B belong to the evolutionary conserved Lgd protein family with members in all multi-cellular animals. Several functions such as centrosomal cleavage, involvement in signalling pathways, immune response and synapse maturation have been described for CC2D1A. Moreover, the Drosophila me...

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Detalles Bibliográficos
Autores principales: Drusenheimer, Nadja, Migdal, Bernhard, Jäckel, Sandra, Tveriakhina, Lena, Scheider, Kristina, Schulz, Katharina, Gröper, Jieny, Köhrer, Karl, Klein, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697852/
https://www.ncbi.nlm.nih.gov/pubmed/26720614
http://dx.doi.org/10.1371/journal.pgen.1005749