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Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type

Small cell carcinoma of the ovary, hypercalcemic type is an aggressive tumor generally affecting young women with limited treatment options. Mutations in SMARCA4, a catalytic subunit of the SWI/SNF chromatin remodeling complex, have recently been identified in nearly all small cell carcinoma of the...

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Detalles Bibliográficos
Autores principales: Jelinic, Petar, Schlappe, Brooke A, Conlon, Niamh, Tseng, Jill, Olvera, Narciso, Dao, Fanny, Mueller, Jennifer J, Hussein, Yaser, Soslow, Robert A, Levine, Douglas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697871/
https://www.ncbi.nlm.nih.gov/pubmed/26564006
http://dx.doi.org/10.1038/modpathol.2015.129