Loss of histone H3 lysine 36 trimethylation is associated with an increased risk of renal cell carcinoma-specific death

Sequencing of clear cell renal cell carcinomas identified loss-of-function mutations of SETD2, a gene that encodes a nonredundant methytransferase responsible for histone H3 lysine 36 trimethylation (H3K36me3), and H3K36me3 is progressively deregulated in metastases. However, few data exist regardin...

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Detalles Bibliográficos
Autores principales: Ho, Thai H., Kapur, Payal, Joseph, Richard W., Serie, Daniel J., Eckel-Passow, Jeanette E., Tong, Pan, Wang, Jing, Castle, Erik P., Stanton, Melissa L., Cheville, John C., Jonasch, Eric, Brugarolas, James, Parker, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697879/
https://www.ncbi.nlm.nih.gov/pubmed/26516698
http://dx.doi.org/10.1038/modpathol.2015.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697879/
https://www.ncbi.nlm.nih.gov/pubmed/26516698
http://dx.doi.org/10.1038/modpathol.2015.123

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