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Single Enzyme Experiments Reveal a Long-Lifetime Proton Leak State in a Heme-Copper Oxidase

[Image: see text] Heme-copper oxidases (HCOs) are key enzymes in prokaryotes and eukaryotes for energy production during aerobic respiration. They catalyze the reduction of the terminal electron acceptor, oxygen, and utilize the Gibbs free energy to transport protons across a membrane to generate a...

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Detalles Bibliográficos
Autores principales: Li, Mengqiu, Jørgensen, Sune K., McMillan, Duncan G. G., Krzemiński, Łukasz, Daskalakis, Nikolaos N., Partanen, Riitta H., Tutkus, Marijonas, Tuma, Roman, Stamou, Dimitrios, Hatzakis, Nikos S., Jeuken, Lars J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697922/
https://www.ncbi.nlm.nih.gov/pubmed/26618221
http://dx.doi.org/10.1021/jacs.5b08798