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Genome-wide Detection of DNase I Hypersensitive Sites in Single Cells and FFPE Samples
DNase I hypersensitive sites (DHSs) provide important information on the presence of transcriptional regulatory elements and the state of chromatin in mammalian cells(1–3). Conventional DNase-Seq for genome-wide DHSs profiling is limited by the requirement of millions of cells(4,5). Here we report a...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697938/ https://www.ncbi.nlm.nih.gov/pubmed/26605532 http://dx.doi.org/10.1038/nature15740 |