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Distinct Characteristics of Small Cell Lung Cancer Correlate With Central or Peripheral Origin: Subtyping Based on Location and Expression of Transcription Factor TTF-1

Small-cell lung carcinoma (SCLC) is a type of lung cancer with neuroendocrine differentiation and a poor prognosis that is widely believed to arise in the central lung. Thyroid transcription factor-1 (TTF-1) is a peripheral marker of lung adenocarcinoma that is also highly expressed in SCLC. In this...

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Detalles Bibliográficos
Autores principales: Miyauchi, Eisaku, Motoi, Noriko, Ono, Hiroshi, Ninomiya, Hironori, Ohyanagi, Fumiyoshi, Nishio, Makoto, Okumura, Sakae, Ichinose, Masakazu, Ishikawa, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697988/
https://www.ncbi.nlm.nih.gov/pubmed/26705222
http://dx.doi.org/10.1097/MD.0000000000002324