Transcriptomics Profiling of Alzheimer’s Disease Reveal Neurovascular Defects, Altered Amyloid-β Homeostasis, and Deregulated Expression of Long Noncoding RNAs

The underlying genetic variations of late-onset Alzheimer’s disease (LOAD) cases remain largely unknown. A combination of genetic variations with variable penetrance and lifetime epigenetic factors may converge on transcriptomic alterations that drive LOAD pathological process. Transcriptome profili...

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Detalles Bibliográficos
Autores principales: Magistri, Marco, Velmeshev, Dmitry, Makhmutova, Madina, Faghihi, Mohammad Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698155/
https://www.ncbi.nlm.nih.gov/pubmed/26402107
http://dx.doi.org/10.3233/JAD-150398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698155/
https://www.ncbi.nlm.nih.gov/pubmed/26402107
http://dx.doi.org/10.3233/JAD-150398

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