A mitochondria-targeted derivative of ascorbate: MitoC

Mitochondrial oxidative damage contributes to a wide range of pathologies. One therapeutic strategy to treat these disorders is targeting antioxidants to mitochondria by conjugation to the lipophilic triphenylphosphonium (TPP) cation. To date only hydrophobic antioxidants have been targeted to mitoc...

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Detalles Bibliográficos
Autores principales: Finichiu, Peter G., Larsen, David S., Evans, Cameron, Larsen, Lesley, Bright, Thomas P., Robb, Ellen L., Trnka, Jan, Prime, Tracy A., James, Andrew M., Smith, Robin A.J., Murphy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698375/
https://www.ncbi.nlm.nih.gov/pubmed/26453920
http://dx.doi.org/10.1016/j.freeradbiomed.2015.07.160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698375/
https://www.ncbi.nlm.nih.gov/pubmed/26453920
http://dx.doi.org/10.1016/j.freeradbiomed.2015.07.160

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