Tibialis Anterior Muscle Needle Biopsy and Sensitive Biomolecular Methods: A Useful Tool in Myotonic Dystrophy Type 1

Myotonic dystrophy type 1 (DM1) is a neuromuscular disorder caused by a CTG repeat expansion in 3’UTR of DMPK gene. This mutation causes accumulation of toxic RNA in nuclear foci leading to splicing misregulation of specific genes. In view of future clinical trials with antisense oligonucleotides in...

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Detalles Bibliográficos
Autores principales: Iachettini, S., Valaperta, R., Marchesi, A., Perfetti, A., Cuomo, G., Fossati, B., Vaienti, L., Costa, E., Meola, G., Cardani, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698615/
https://www.ncbi.nlm.nih.gov/pubmed/26708183
http://dx.doi.org/10.4081/ejh.2015.2562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698615/
https://www.ncbi.nlm.nih.gov/pubmed/26708183
http://dx.doi.org/10.4081/ejh.2015.2562

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