Structural basis of lantibiotic recognition by the nisin resistance protein from Streptococcus agalactiae

Lantibiotics are potent antimicrobial peptides. Nisin is the most prominent member and contains five crucial lanthionine rings. Some clinically relevant bacteria express membrane-associated resistance proteins that proteolytically inactivate nisin. However, substrate recognition and specificity of t...

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Detalles Bibliográficos
Autores principales: Khosa, Sakshi, Frieg, Benedikt, Mulnaes, Daniel, Kleinschrodt, Diana, Hoeppner, Astrid, Gohlke, Holger, Smits, Sander H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698656/
https://www.ncbi.nlm.nih.gov/pubmed/26727488
http://dx.doi.org/10.1038/srep18679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698656/
https://www.ncbi.nlm.nih.gov/pubmed/26727488
http://dx.doi.org/10.1038/srep18679

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