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IL-1 Receptor Blockade Alleviates Graft-versus-Host Disease through Downregulation of an Interleukin-1β-Dependent Glycolytic Pathway in Th17 Cells

T helper (Th) 17 cells are a subset of Th cells expressing interleukin- (IL-) 17 and initiating an inflammatory response in autoimmune diseases. Graft-versus-host disease (GVHD) is an immune inflammatory disease caused by interactions between the adaptive immunity of donor and recipient. The Th17 li...

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Detalles Bibliográficos
Autores principales: Park, Min-Jung, Lee, Seung Hoon, Lee, Sung-Hee, Lee, Eun-Jung, Kim, Eun-Kyung, Choi, Jong Young, Cho, Mi-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698788/
https://www.ncbi.nlm.nih.gov/pubmed/26798206
http://dx.doi.org/10.1155/2015/631384