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Vpx-containing Dendritic Cell Vaccine Vectors Induce CTLs and Reactivate Latent HIV-1 in vitro

Eradication of HIV-1 from an infected individual requires a means of inducing production of virus from latently infected cells and stimulating an immune response against the infected cells. We report the development of lentiviral vectors that transduce dendritic cells (DCs) to both induce production...

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Detalles Bibliográficos
Autores principales: Norton, Thomas D., Miller, Elizabeth A., Bhardwaj, Nina, Landau, Nathaniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698816/
https://www.ncbi.nlm.nih.gov/pubmed/25567537
http://dx.doi.org/10.1038/gt.2014.117