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Development and evaluation of in situ nasal gel formulations of loratadine

The objective of the present work was to formulate and evaluate mucoadhesive in situ nasal gels of loratadine. This drug delivery system may overcome the first-pass metabolism and subsequently improve the bioavailability of the drug. A total of 16 formulations of in situ nasal gels were prepared usi...

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Detalles Bibliográficos
Autores principales: Sherafudeen, Sheri Peedikayil, Vasantha, Prasanth Viswanadhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698857/
https://www.ncbi.nlm.nih.gov/pubmed/26779266