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Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity

Obesity is associated with immunological perturbations that contribute to insulin resistance. Epigenetic mechanisms can control immune functions and have been linked to metabolic complications, although their contribution to insulin resistance still remains unclear. In this study, we investigated th...

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Detalles Bibliográficos
Autores principales: Jacobsen, Mette J., Mentzel, Caroline M. Junker, Olesen, Ann Sofie, Huby, Thierry, Jørgensen, Claus B., Barrès, Romain, Fredholm, Merete, Simar, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698937/
https://www.ncbi.nlm.nih.gov/pubmed/26798656
http://dx.doi.org/10.1155/2016/8539057