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Renal Protection by Genetic Deletion of the Atypical Chemokine Receptor ACKR2 in Diabetic OVE Mice

In diabetic nephropathy (DN) proinflammatory chemokines and leukocyte infiltration correlate with tubulointerstitial injury and declining renal function. The atypical chemokine receptor ACKR2 is a chemokine scavenger receptor which binds and sequesters many inflammatory CC chemokines but does not tr...

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Detalles Bibliográficos
Autores principales: Zheng, Shirong, Coventry, Susan, Cai, Lu, Powell, David W., Jala, Venkatakrishna R., Haribabu, Bodduluri, Epstein, Paul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699014/
https://www.ncbi.nlm.nih.gov/pubmed/26798651
http://dx.doi.org/10.1155/2016/5362506