The Plant-Derived Chalcone 2,2′,5′-Trihydroxychalcone Provides Neuroprotection against Toll-Like Receptor 4 Triggered Inflammation in Microglia

Chalcones are plant metabolites with potential for therapeutic exploitation as antioxidant, anti-inflammatory, and antiproliferative agents. Here we explored the neuroprotective effects of 2,2′,5′-trihydroxychalcone (225THC), a potent antioxidant with radical-scavenging properties. 225THC was found...

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Detalles Bibliográficos
Autores principales: Jiwrajka, Manasi, Phillips, Alexandra, Butler, Matt, Rossi, Miriam, Pocock, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699027/
https://www.ncbi.nlm.nih.gov/pubmed/26798424
http://dx.doi.org/10.1155/2016/6301712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699027/
https://www.ncbi.nlm.nih.gov/pubmed/26798424
http://dx.doi.org/10.1155/2016/6301712

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