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Improved Chromatographic Separation of Sitagliptin Phosphate and Metformin Hydrochloride
New UPLC method was developed for determination of sitagliptin and metformin using Symmetry C(18) column (100 mm × 2.1 mm, 2.2 μm) and isocratic elution (methanol 20%), pH (3.5) as a mobile phase. The ultraviolet detector was operated at 220 nm and the column temperature was 50°C. Linearity paramete...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Master Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699135/ https://www.ncbi.nlm.nih.gov/pubmed/26759536 |