REST/NRSF Knockdown Alters Survival, Lineage Differentiation and Signaling in Human Embryonic Stem Cells

REST (RE1 silencing transcription factor), also known as NRSF (neuron-restrictive silencer factor), is a well-known transcriptional repressor of neural genes in non-neural tissues and stem cells. Dysregulation of REST activity is thought to play a role in diverse diseases including epilepsy, cancer,...

Descripción completa

Detalles Bibliográficos
Autores principales: Thakore-Shah, Kaushali, Koleilat, Tasneem, Jan, Majib, John, Alan, Pyle, April D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699193/
https://www.ncbi.nlm.nih.gov/pubmed/26690059
http://dx.doi.org/10.1371/journal.pone.0145280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699193/
https://www.ncbi.nlm.nih.gov/pubmed/26690059
http://dx.doi.org/10.1371/journal.pone.0145280

Ejemplares similares