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Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation
BACKGROUND: CpG methylation variation is involved in human trait formation and disease susceptibility. Analyses within populations have been biased towards CpG-dense regions through the application of targeted arrays. We generate whole-genome bisulfite sequencing data for approximately 30 adipose an...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699357/ https://www.ncbi.nlm.nih.gov/pubmed/26699896 http://dx.doi.org/10.1186/s13059-015-0856-1 |