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Local compartment changes and regulatory landscape alterations in histone H1-depleted cells

BACKGROUND: Linker histone H1 is a core chromatin component that binds to nucleosome core particles and the linker DNA between nucleosomes. It has been implicated in chromatin compaction and gene regulation and is anticipated to play a role in higher-order genome structure. Here we have used a combi...

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Detalles Bibliográficos
Autores principales: Geeven, Geert, Zhu, Yun, Kim, Byung Ju, Bartholdy, Boris A., Yang, Seung-Min, Macfarlan, Todd S., Gifford, Wesley D., Pfaff, Samuel L., Verstegen, Marjon J. A. M., Pinto, Hugo, Vermunt, Marit W., Creyghton, Menno P., Wijchers, Patrick J., Stamatoyannopoulos, John A., Skoultchi, Arthur I., de Laat, Wouter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699363/
https://www.ncbi.nlm.nih.gov/pubmed/26700097
http://dx.doi.org/10.1186/s13059-015-0857-0