Prostaglandin E(2) stimulates normal bronchial epithelial cell growth through induction of c-Jun and PDK1, a kinase implicated in oncogenesis

BACKGROUND: Cyclooxygenase-2-derived prostaglandin E(2) (PGE(2)), a bioactive eicosanoid, has been implicated in many biological processes including reproduction, inflammation and tumor growth. We previously showed that PGE(2) stimulated lung cancer cell growth and progression through PGE(2) recepto...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Yu, Wang, Ye, Wang, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699375/
https://www.ncbi.nlm.nih.gov/pubmed/26684827
http://dx.doi.org/10.1186/s12931-015-0309-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699375/
https://www.ncbi.nlm.nih.gov/pubmed/26684827
http://dx.doi.org/10.1186/s12931-015-0309-0

Ejemplares similares