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Erythropoietin and IGF-1 signaling synchronize cell proliferation and maturation during erythropoiesis
Tight coordination of cell proliferation and differentiation is central to red blood cell formation. Erythropoietin controls the proliferation and survival of red blood cell precursors, while variations in GATA-1/FOG-1 complex composition and concentrations drive their maturation. However, clear evi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699388/ https://www.ncbi.nlm.nih.gov/pubmed/26680303 http://dx.doi.org/10.1101/gad.267633.115 |