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Genome-wide screen uncovers novel pathways for tRNA processing and nuclear–cytoplasmic dynamics

Transfer ribonucleic acids (tRNAs) are essential for protein synthesis. However, key gene products involved in tRNA biogenesis and subcellular movement remain to be discovered. We conducted the first comprehensive unbiased analysis of the role of nearly an entire proteome in tRNA biology and describ...

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Detalles Bibliográficos
Autores principales: Wu, Jingyan, Bao, Alicia, Chatterjee, Kunal, Wan, Yao, Hopper, Anita K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699390/
https://www.ncbi.nlm.nih.gov/pubmed/26680305
http://dx.doi.org/10.1101/gad.269803.115