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Expansion of quiescent lung adenocarcinoma CD8(+) T cells by MUC1-8-mer peptide-T2 cell-β2 microglobulin complexes

Adoptive immunotherapy requires the isolation of CD8(+) T cells specific for tumor-associated antigens, their expansion in vitro and their transfusion to the patient to mediate a therapeutic effect. MUC1 is an important adenocarcinoma antigen immunogenic for T cells. The MUC1-derived SAPDTRPA (MUC1-...

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Detalles Bibliográficos
Autores principales: ATZIN-MÉNDEZ, J.A., LÓPEZ-GONZÁLEZ, J.S., BÁEZ, R., ARENAS-DEL ANGEL, M.C., MONTAÑO, L.F., SILVA-ADAYA, D., LASCURAIN, R., GOROCICA, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699617/
https://www.ncbi.nlm.nih.gov/pubmed/26498650
http://dx.doi.org/10.3892/or.2015.4328