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Changes in Practice Patterns of Clopidogrel in Combination with Proton Pump Inhibitors after an FDA Safety Communication

OBJECTIVES: In 2009, the FDA issued a warning that omeprazole–a proton pump inhibitor (PPI)–reduces the antithrombotic effect of clopidogrel by almost half when taken concomitantly. This study aims to analyze the impact of the FDA Safety Communications on prescribing clopidogrel together with PPIs....

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Detalles Bibliográficos
Autores principales: Guérin, Annie, Mody, Reema, Carter, Valerie, Ayas, Charles, Patel, Haridarshan, Lasch, Karen, Wu, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699636/
https://www.ncbi.nlm.nih.gov/pubmed/26727382
http://dx.doi.org/10.1371/journal.pone.0145504