Papillomavirus-Associated Tumor Formation Critically Depends on c-Fos Expression Induced by Viral Protein E2 and Bromodomain Protein Brd4

We investigated the mechanism of how the papillomavirus E2 transcription factor can activate promoters through activator protein (AP)1 binding sites. Using an unbiased approach with an inducible cell line expressing the viral transcription factor E2 and transcriptome analysis, we found that E2 induc...

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Detalles Bibliográficos
Autores principales: Delcuratolo, Maria, Fertey, Jasmin, Schneider, Markus, Schuetz, Johanna, Leiprecht, Natalie, Hudjetz, Benjamin, Brodbeck, Stephan, Corall, Silke, Dreer, Marcel, Schwab, Roxana Michaela, Grimm, Martin, Wu, Shwu-Yuan, Stubenrauch, Frank, Chiang, Cheng-Ming, Iftner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699637/
https://www.ncbi.nlm.nih.gov/pubmed/26727473
http://dx.doi.org/10.1371/journal.ppat.1005366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699637/
https://www.ncbi.nlm.nih.gov/pubmed/26727473
http://dx.doi.org/10.1371/journal.ppat.1005366

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