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Pore Structure and Synergy in Antimicrobial Peptides of the Magainin Family

Magainin 2 and PGLa are among the best-studied cationic antimicrobial peptides. They bind preferentially to negatively charged membranes and apparently cause their disruption by the formation of transmembrane pores, whose detailed structure is still unclear. Here we report the results of 5–9 μs all-...

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Detalles Bibliográficos
Autores principales: Pino-Angeles, Almudena, Leveritt, John M., Lazaridis, Themis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699650/
https://www.ncbi.nlm.nih.gov/pubmed/26727376
http://dx.doi.org/10.1371/journal.pcbi.1004570