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Pore Structure and Synergy in Antimicrobial Peptides of the Magainin Family
Magainin 2 and PGLa are among the best-studied cationic antimicrobial peptides. They bind preferentially to negatively charged membranes and apparently cause their disruption by the formation of transmembrane pores, whose detailed structure is still unclear. Here we report the results of 5–9 μs all-...
Autores principales: | Pino-Angeles, Almudena, Leveritt, John M., Lazaridis, Themis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699650/ https://www.ncbi.nlm.nih.gov/pubmed/26727376 http://dx.doi.org/10.1371/journal.pcbi.1004570 |
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