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Coordination of Hepatitis C Virus Assembly by Distinct Regulatory Regions in Nonstructural Protein 5A

Hepatitis C virus (HCV) nonstructural protein (NS)5A is a RNA-binding protein composed of a N-terminal membrane anchor, a structured domain I (DI) and two intrinsically disordered domains (DII and DIII) interacting with viral and cellular proteins. While DI and DII are essential for RNA replication,...

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Detalles Bibliográficos
Autores principales: Zayas, Margarita, Long, Gang, Madan, Vanesa, Bartenschlager, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699712/
https://www.ncbi.nlm.nih.gov/pubmed/26727512
http://dx.doi.org/10.1371/journal.ppat.1005376