Nitric Oxide-cGMP Signaling Stimulates Erythropoiesis through Multiple Lineage-Specific Transcription Factors: Clinical Implications and a Novel Target for Erythropoiesis

Much attention has been directed to the physiological effects of nitric oxide (NO)-cGMP signaling, but virtually nothing is known about its hematologic effects. We reported for the first time that cGMP signaling induces human γ-globin gene expression. Aiming at developing novel therapeutics for anem...

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Detalles Bibliográficos
Autores principales: Ikuta, Tohru, Sellak, Hassan, Odo, Nadine, Adekile, Adekunle D., Gaensler, Karin M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699757/
https://www.ncbi.nlm.nih.gov/pubmed/26727002
http://dx.doi.org/10.1371/journal.pone.0144561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699757/
https://www.ncbi.nlm.nih.gov/pubmed/26727002
http://dx.doi.org/10.1371/journal.pone.0144561

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