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Renal Ischemia/Reperfusion Injury in Soluble Epoxide Hydrolase-Deficient Mice

AIM: 20-hydroxyeicosatetraenoic acid (20-HETE) and epoxyeicosatrienoic acids (EETs) are cytochrome P450 (CYP)-dependent eicosanoids that play opposite roles in the regulation of vascular tone, inflammation, and apoptosis. 20-HETE aggravates, whereas EETs ameliorate ischemia/reperfusion (I/R)-induced...

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Detalles Bibliográficos
Autores principales: Zhu, Ye, Blum, Maximilian, Hoff, Uwe, Wesser, Tim, Fechner, Mandy, Westphal, Christina, Gürgen, Dennis, Catar, Rusan Ali, Philippe, Aurelie, Wu, Kaiyin, Bubalo, Gordana, Rothe, Michael, Weldon, Steven M., Dragun, Duska, Schunck, Wolf-Hagen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699807/
https://www.ncbi.nlm.nih.gov/pubmed/26727266
http://dx.doi.org/10.1371/journal.pone.0145645