Epigenetic Segregation of Microbial Genomes from Complex Samples Using Restriction Endonucleases HpaII and McrB

We describe continuing work to develop restriction endonucleases as tools to enrich targeted genomes of interest from diverse populations. Two approaches were developed in parallel to segregate genomic DNA based on cytosine methylation. First, the methyl-sensitive endonuclease HpaII was used to bind...

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Detalles Bibliográficos
Autores principales: Liu, Guohong, Weston, Christopher Q., Pham, Long K., Waltz, Shannon, Barnes, Helen, King, Paula, Sphar, Dan, Yamamoto, Robert T., Forsyth, R. Allyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699840/
https://www.ncbi.nlm.nih.gov/pubmed/26727463
http://dx.doi.org/10.1371/journal.pone.0146064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699840/
https://www.ncbi.nlm.nih.gov/pubmed/26727463
http://dx.doi.org/10.1371/journal.pone.0146064

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