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Synthetic prions with novel strain-specified properties

Prions are infectious proteins that possess multiple self-propagating structures. The information for strains and structural specific barriers appears to be contained exclusively in the folding of the pathological isoform, PrP(Sc). Many recent studies determined that de novo prion strains could be g...

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Detalles Bibliográficos
Autores principales: Moda, Fabio, T. Le, Thanh-Nhat, Aulić, Suzana, Bistaffa, Edoardo, Campagnani, Ilaria, Virgilio, Tommaso, Indaco, Antonio, Palamara, Luisa, Andréoletti, Olivier, Tagliavini, Fabrizio, Legname, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699842/
https://www.ncbi.nlm.nih.gov/pubmed/26720726
http://dx.doi.org/10.1371/journal.ppat.1005354