Cargando…

Synthetic prions with novel strain-specified properties

Prions are infectious proteins that possess multiple self-propagating structures. The information for strains and structural specific barriers appears to be contained exclusively in the folding of the pathological isoform, PrP(Sc). Many recent studies determined that de novo prion strains could be g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moda, Fabio, T. Le, Thanh-Nhat, Aulić, Suzana, Bistaffa, Edoardo, Campagnani, Ilaria, Virgilio, Tommaso, Indaco, Antonio, Palamara, Luisa, Andréoletti, Olivier, Tagliavini, Fabrizio, Legname, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699842/ https://www.ncbi.nlm.nih.gov/pubmed/26720726 http://dx.doi.org/10.1371/journal.ppat.1005354

Ejemplares similares

α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication
por: Aulić, Suzana, et al.
Publicado: (2017)

Defined α-synuclein prion-like molecular assemblies spreading in cell culture
por: Aulić, Suzana, et al.
Publicado: (2014)

The Cellular Prion Protein Increases the Uptake and Toxicity of TDP-43 Fibrils
por: Scialò, Carlo, et al.
Publicado: (2021)

Contributions of Molecular and Optical Techniques to the Clinical Diagnosis of Alzheimer’s Disease
por: Bistaffa, Edoardo, et al.
Publicado: (2020)

Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia
por: Redaelli, Veronica, et al.
Publicado: (2017)

Different tau fibril types reduce prion level in chronically and de novo infected cells
por: Celauro, Luigi, et al.
Publicado: (2023)

Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids
por: Bistaffa, Edoardo, et al.
Publicado: (2019)

Differential overexpression of SERPINA3 in human prion diseases
por: Vanni, S., et al.
Publicado: (2017)

Molecular subtypes of Alzheimer’s disease
por: Di Fede, Giuseppe, et al.
Publicado: (2018)

PMCA-generated prions from the olfactory mucosa of patients with Fatal Familial Insomnia cause prion disease in mice
por: Bistaffa, Edoardo, et al.
Publicado: (2021)

Tackling amyloidogenesis in Alzheimer’s disease with A2V variants of Amyloid-β
por: Di Fede, Giuseppe, et al.
Publicado: (2016)

Serpin Signatures in Prion and Alzheimer’s Diseases
por: Zattoni, Marco, et al.
Publicado: (2022)

Site-specific analysis of N-glycans from different sheep prion strains
por: Nakić, Natali, et al.
Publicado: (2021)

Correction: Site-specific analysis of N-glycans from different sheep prion strains
por: Nakić, Natali, et al.
Publicado: (2021)

Structural and dynamical determinants of a β-sheet-enriched intermediate involved in amyloid fibrillar assembly of human prion protein
por: Russo, Luigi, et al.
Publicado: (2022)

Clinical and neuropathological phenotype associated with the novel V189I mutation in the prion protein gene
por: Di Fede, Giuseppe, et al.
Publicado: (2019)

Small-Molecule Theranostic Probes: A Promising Future in Neurodegenerative Diseases
por: Aulić, Suzana, et al.
Publicado: (2013)

Sporadic Creutzfeldt-Jakob disease: Real-Time Quaking-Induced Conversion (RT-QuIC) assay represents a major diagnostic advance
por: Cazzaniga, Federico Angelo, et al.
Publicado: (2021)

Protease-Sensitive Synthetic Prions
por: Colby, David W., et al.
Publicado: (2010)

PMCA-Based Detection of Prions in the Olfactory Mucosa of Patients With Sporadic Creutzfeldt–Jakob Disease
por: Cazzaniga, Federico Angelo, et al.
Publicado: (2022)

Corrigendum: PMCA-based detection of prions in the olfactory mucosa of patients with sporadic Creutzfeldt–Jakob disease
por: Cazzaniga, Federico Angelo, et al.
Publicado: (2023)

Copper coordination modulates prion conversion and infectivity in mammalian prion proteins
por: Legname, Giuseppe
Publicado: (2023)

Elucidating the function of the prion protein
por: Legname, Giuseppe
Publicado: (2017)

Prion protein and aging
por: Gasperini, Lisa, et al.
Publicado: (2014)

Mapping the Prion Protein Distribution in Marsupials: Insights from Comparing Opossum with Mouse CNS
por: Poggiolini, Ilaria, et al.
Publicado: (2012)

Translational Research in Alzheimer’s and Prion Diseases
por: Di Fede, Giuseppe, et al.
Publicado: (2018)

Impact of seed amplification assay and surface-enhanced Raman spectroscopy combined approach on the clinical diagnosis of Alzheimer’s disease
por: D’Andrea, Cristiano, et al.
Publicado: (2023)

De novo prions
por: Benetti, Federico, et al.
Publicado: (2010)

Host prion protein expression levels impact prion tropism for the spleen
por: Béringue, Vincent, et al.
Publicado: (2020)

Prion and Prion-Like Protein Strains: Deciphering the Molecular Basis of Heterogeneity in Neurodegeneration
por: Scialò, Carlo, et al.
Publicado: (2019)

Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson’s disease and multiple system atrophy
por: De Luca, Chiara Maria Giulia, et al.
Publicado: (2019)

Mammalian prion propagation in PrP transgenic Drosophila
por: Thackray, Alana M, et al.
Publicado: (2018)

Prion disease modelled in Drosophila
por: Bujdoso, Raymond, et al.
Publicado: (2022)

The Efficacy of Tetracyclines in Peripheral and Intracerebral Prion Infection
por: De Luigi, Ada, et al.
Publicado: (2008)

Structural Consequences of Copper Binding to the Prion Protein
por: Salzano, Giulia, et al.
Publicado: (2019)

The Alpha-Synuclein RT-QuIC Products Generated by the Olfactory Mucosa of Patients with Parkinson’s Disease and Multiple System Atrophy Induce Inflammatory Responses in SH-SY5Y Cells
por: De Luca, Chiara Maria Giulia, et al.
Publicado: (2021)

Porcine Prion Protein as a Paradigm of Limited Susceptibility to Prion Strain Propagation
por: Espinosa, Juan Carlos, et al.
Publicado: (2020)

New insights into structural determinants of prion protein folding and stability
por: Benetti, Federico, et al.
Publicado: (2015)

Erratum to: Porcine Prion Protein as a Paradigm of Limited Susceptibility to Prion Strain Propagation
por: Espinosa, Juan Carlos, et al.
Publicado: (2020)

The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion
por: Giachin, Gabriele, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_o2b0hajg9srqevimts1epro8sp