The Nucleotide-Binding Sites of SUR1: A Mechanistic Model

ATP-sensitive potassium (K(ATP)) channels comprise four pore-forming Kir6.2 subunits and four modulatory sulfonylurea receptor (SUR) subunits. The latter belong to the ATP-binding cassette family of transporters. K(ATP) channels are inhibited by ATP (or ADP) binding to Kir6.2 and activated by Mg-nuc...

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Detalles Bibliográficos
Autores principales: Vedovato, Natascia, Ashcroft, Frances M., Puljung, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2015
Materias:
Biophysical Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699857/
https://www.ncbi.nlm.nih.gov/pubmed/26682803
http://dx.doi.org/10.1016/j.bpj.2015.10.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699857/
https://www.ncbi.nlm.nih.gov/pubmed/26682803
http://dx.doi.org/10.1016/j.bpj.2015.10.026

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