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The Nucleotide-Binding Sites of SUR1: A Mechanistic Model
ATP-sensitive potassium (K(ATP)) channels comprise four pore-forming Kir6.2 subunits and four modulatory sulfonylurea receptor (SUR) subunits. The latter belong to the ATP-binding cassette family of transporters. K(ATP) channels are inhibited by ATP (or ADP) binding to Kir6.2 and activated by Mg-nuc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699857/ https://www.ncbi.nlm.nih.gov/pubmed/26682803 http://dx.doi.org/10.1016/j.bpj.2015.10.026 |