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Roles of Asp179 and Glu270 in ADP-Ribosylation of Actin by Clostridium perfringens Iota Toxin
Clostridium perfringens iota toxin is a binary toxin composed of the enzymatically active component Ia and receptor binding component Ib. Ia is an ADP-ribosyltransferase, which modifies Arg177 of actin. The previously determined crystal structure of the actin-Ia complex suggested involvement of Asp1...
Autores principales: | Belyy, Alexander, Tabakova, Irina, Lang, Alexander E., Jank, Thomas, Belyi, Yury, Aktories, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699905/ https://www.ncbi.nlm.nih.gov/pubmed/26713879 http://dx.doi.org/10.1371/journal.pone.0145708 |
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