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Disrupted PI3K p110δ Signaling Dysregulates Maternal Immune Cells and Increases Fetal Mortality In Mice

Maternal immune cells are an integral part of reproduction, but how they might cause pregnancy complications remains elusive. Macrophages and their dual function in inflammation and tissue repair are thought to play key yet undefined roles. Altered perinatal growth underpins adult morbidity, and nat...

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Detalles Bibliográficos
Autores principales: Kieckbusch, Jens, Balmas, Elisa, Hawkes, Delia A., Colucci, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700049/
https://www.ncbi.nlm.nih.gov/pubmed/26711346
http://dx.doi.org/10.1016/j.celrep.2015.11.050